Home  
  Our Team  
  Patient Info  
  Services  
  Bill Payment  
Sean Boyle, MD
Sean Boyle, MD
Biography

News for Healthier Living

Prescription Opioids May Raise Pneumonia Risk

THURSDAY, Jan. 10, 2019 (HealthDay News) -- People who take prescription opioid painkillers are at increased risk for pneumonia, especially those with HIV, a new study suggests.

The findings support concerns that prescription opioids can weaken the immune system. Doctors who prescribe opioids need to reduce patients' risk of pneumonia through vaccination and by encouraging them to stop smoking, the researchers said.

For the study, a team from Yale University analyzed data from U.S. patients with and without HIV who were treated at Veterans Affairs medical facilities between 2000 and 2012.

Patients prescribed medium or high doses of opioid painkillers had a higher risk of pneumonia than those who did not take the medications, the findings showed. The risk was highest among those who took immunosuppressive opioids, such as codeine, fentanyl and morphine.

Patients with HIV were more likely to develop pneumonia even when taking low doses of opioids, and especially if they took immunosuppressive opioids, the investigators found.

"We saw that prescription opioids were independently associated with pneumonia requiring hospitalization," said corresponding author Dr. E. Jennifer Edelman, an associate professor at Yale School of Medicine.

Opioids are commonly prescribed to treat pain, especially among patients with HIV, the researchers noted. They believe this is the first study to look at how prescription opioids affect pneumonia risk in patients with HIV.

Prescription opioids can weaken the immune system's ability to fight pneumonia in a number of ways, including by suppressing cough, respiration and mucus secretion, according to the researchers.

The report "lends credence to the hypothesis that opioids have effects on the immune system that are clinically relevant," Edelman said in a Yale news release.

The study was published Jan. 7 in JAMA Internal Medicine.

To reduce the risk of pneumonia, prescribers should consider lower doses of opioids or opioids that do not suppress the immune system, the researchers said. They also suggested that health care providers encourage pneumonia vaccination for patients, especially those with HIV.

More information

The U.S. Centers for Disease Control and Prevention has more on opioids.

January 10, 2019
Copyright © 2019 HealthDay. All rights reserved.


March 21 2019

March 20 2019

March 19 2019

March 18 2019

March 15 2019

March 14 2019

March 13 2019

March 12 2019

March 11 2019

March 10 2019

March 9 2019

March 8 2019

Patient Portal Access


Copyright HealthBanks, Inc. All rights reserved. | Terms of Use | Privacy Policy